The math is out there somewhere and I know the all around best ratio is a 3 Wolf, 2 Bolt to maximize consistency while minimizing early game bricking. 3 and 3 is more consistent to get the combo pieces but has a much higher chance of having a hand that flops the first two turns. 3-3 is still fine to run though because it doesn't pose as much of a risk to draw your only two Bolts, ruining the combo. It's unlikely, but obviously more likely than drawing all three.
EDIT: Found it.